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Fig. 12 | Biological Research

Fig. 12

From: Endocannabinoid system upregulates the enrichment and differentiation of human iPSC- derived spermatogonial stem cells via CB2R agonism

Fig. 12

CB65 induces differentiation of hSSCs. CB65 at submaximal dose A, C. increases the ratio of ID4+, PLZF + hSSCs on day 10 and B, C. does not influence the ratio of SCP3+, ACR + hSSCs on day 12 compared to controls by FCM. D. On day 10, all groups present a similar ID4 and PLZF expression pattern compared to controls. On day 12, CB65 applied group presents a higher SCP3 and a similar ACR expression compared to controls. * p < 0.05

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