Fig. 5
Testicular pathology and fecundity in mice. A, B Testis by hematoxylin–eosin (HE) staining. A HE staining of testis of wild-type mice. B HE staining of testis of Cul4bL337M male mice. C The numbers of pups per litter of wild-type mice and Cul4bL337M mutant male mice crossed with wild-type female mice (n > 20; mean ± SD; *p < 0.05, ** p < 0.01 and ***p < 0.001)