Fig. 1

Workflow of the Regional Hereditary Cancer Program implemented for Hospital Regional de Talca of the Maule Region. The main map of Chile indicates the location of the Maule Region where the program is implemented. The program compiles detailed information on each patient recruited into the Hereditary Cancer Program into an exclusive database. This information includes personal history, clinical history of pathological anatomy, and genetic counseling details. The latter encompasses patient identification, age, sex, age at diagnosis, type of cancer, histology, molecular subtype, presence of first-degree and second-degree relatives, among other data. Additionally, the database records the variants identified through genetic testing