Fig. 6

Reelin-positive layer I of the fetal brain: (a) – in the calcarine sulcus at 16 gw (Cas); (b) – in the parietooccipital sulcus at 16 gw (Pos), right hemisphere, coronal section; (c) – in the calcarine sulcus at 26 gw (Cas); (d) – in the parietooccipital sulcus at 26 gw (Pos), right hemisphere, coronal section. Dark-stained Cajal–Retzius cells were revealed. Scale bar: 50 μm. (e) – Reelin-immunoreactivity coefficient in early fetal (ef), middle fetal (mf) and late fetal (lf) periods. (f) – Reelin-immunoreactivity coefficient at different stages: provisional sulci; the parietooccipital sulcus smoothing stage (Pos-); two sulci, when both sulci exist; the calcarine sulcus smoothing stage (Cas-); permanent sulci. (g) – Reelin-immunoreactivity coefficient of the layer I at various gestational ages for calcarine sulcus and parietooccipital sulcus. Significant differences between sulci are marked by square brackets and asterisks (***p < 0.0001). (h) – Reelin-immunopositive cells in the deep cortical layers, 20 gw. Scale bar: 10 μm