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Table 2 Gene and protein expressions of inflammatory factors in female Wistar and HTG rats

From: Female prediabetic rats are protected from vascular dysfunction: the role of nitroso and sulfide signaling

Parameters

Aorta W

Aorta HTG

PVAT W

PVAT HTG

COX2 (Density COX2/β-actin)

6.30 ± 0.45

9.77 ± 0.37***

0.59 ± 0.03

1.01 ± 0.09+

ICAM (Density ICAM/β-actin)

2.39 ± 0.26

4.35 ± 0.26***

5.99 ± 0.12

5.44 ± 0.16+

Mcp-1mRNA (2-ddCt)

1.00 ± 0.15

0.69 ± 0.29

1.00 ± 0.31

1.74 ± 0.31

Mcp-1 (Density Mcp-1/β-actin)

0.77 ± 0.13

1.86 ± 0.21***

0.66 ± 0.05

0.50 ± 0.03+

TNFαmRNA (2-ddCt)

1.00 ± 0.24

0.27 ± 0.03*

1.00 ± 0.37

0.60 ± 0.15

TNFα (Density TNFα/β-actin)

0.98 ± 0.10

3.50 ± 0.17***

1.03 ± 0.15

6.08 ± 0.26+++

NFκBmRNA (2-ddCt)

1.00 ± 0.17

1.40 ± 0.28

1.00 ± 0.15

1.17 ± 0.18

NFκB (Density NFκB/β-actin)

6.31 ± 0.17

10.48 ± 0.23***

3.40 ± 0.26

7.96 ± 0.58+++

  1. COX2 cyclooxygenase 2, ICAM intercellular adhesion molecule, Mcp-1 monocyte chemoattractant protein-1, TNFα tumor necrosis factor alpha, NfκB nuclear factor kappa B, W Wistar female rats, HTG hereditary hypertriglyceridemic female rats, PVAT perivascular adipose tissue The results are presented as the mean ±S.E.M., and differences between groups were analyzed by one-way ANOVA. *p < 0.05 vs aorta W, ***p < 0.001 vs aorta W, +p < 0.05 vs PVAT W, +++p < 0.001 vs PVAT W