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Table 1 Cardiorespiratory variables during NN and HH in Veh and OXY animals

From: Effect of chronic exogenous oxytocin administration on exercise performance and cardiovagal control in hypobaric hypoxia in rats

 

Veh (n = 6)

OXY (n = 6)

ΔHH test (HH–NN)

 

NN

HH

NN

HH

Veh (n = 6)

OXY (n = 6)

SBP (mmHg)

74.5 ± 10.8

79.5 ± 8.8

85.8 ± 6.5

68.7 ± 5.7*

4.9 ± 3.1

-17.1 ± 9.9+

DBP (mmHg)

42.3 ± 3.6

44.6 ± 3.7

62.2 ± 11.4

50.0 ± 9.6

2.2 ± 4.4

-12.5 ± 10.9

MABP (mmHg)

52.9 ± 5.5

56.1 ± 3.5

70.0 ± 9.5

55.9 ± 8.2

3.1 ± 3.9

-14.0 ± 10.5

PP (mmHg)

32.2 ± 8.6

34.9 ± 10.1

23.6 ± 6.6

18.7 ± 4.5*

2.7 ± 1.6

-4.6 ± 2.6+

HR (beats/min)

246.6 ± 18.0

269.2 ± 22.1

297.4 ± 14.4

226.1 ± 25.6

2.5 ± 29.2

-71.4 ± 28.3+

V̇T (mL)

0.37 ± 0.08

0.48 ± 0.01

0.44 ± 0.13

0.55 ± 0.15*

0.11 ± 0.12

0.10 ± 0.03

Rf (breaths/min)

82.7 ± 6.7

94.9 ± 7.3*

87.7 ± 15.8

99.5 ± 16.1*

12.1 ± 0.7

11.7 ± 0.2

V̇E (mL/min)

30.2 ± 6.8

45.1 ± 11.4*

33.0 ± 7.5

46.3 ± 9.5*

15.0 ± 2.6

13.5 ± 8.3

  1. Data are shown as mean ± standard error of the mean (SEM). NN: normobaric normoxia (PO2: 155 mmHg); HH: hypobaric hypoxia (PO2: 100 mmHg); Veh: vehicle group; OXY: oxytocin group; SBP: systolic blood pressure; DBP: diastolic blood pressure; MABP: mean arterial blood pressure; PP: pulse pressure; HR: heart rate; V̇T: tidal volume; Rf: respiratory frequency; and V̇E: minute ventilation. ΔHH test (HH–NN): the difference between HH and HH. The data was analyzed using repeated measures ANOVA (2 × 2) followed by Holm-Sidak posthoc. The pairs comparison (ΔHH test) was analyzed using the Mann-Whitney test. *, p < 0.05, HH vs. NN; +, p < 0.05, OXY vs. Veh
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Biological Research

ISSN: 0717-6287

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