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Table 1 Results of gene ontology functional enrichment analysis of differentially expressed genes in acute respiratory distress syndrome (ARDS) (Top 12 listed)

From: Candidate genes and pathogenesis investigation for sepsis-related acute respiratory distress syndrome based on gene expression profile

  

GO ID

Term

Count

P value

BP

Up-regulate

GO:0000278

Mitotic cell cycle

26

1.70E−09

GO:1903047

Mitotic cell cycle process

24

2.05E−09

Down-regulate

GO:0048584

Positive regulation of response to stimulus

20

1.31E−05

GO:0033029

Regulation of neutrophil apoptotic process

2

4.80E−05

CC

Up-regulate

GO:0005737

Cytoplasm

89

5.94E−07

GO:0005819

Spindle

11

1.56E−06

Down-regulate

GO:0005819

Spindle

5

0.0055

GO:0005829

Cytosol

20

0.0092

MF

Up-regulate

GO:0019899

Enzyme binding

26

4.22E−06

GO:0019900

Kinase binding

12

0.000143101

Down-regulate

GO:0008329

Signaling pattern recognition receptor activity

2

0.002

GO:0038187

Pattern recognition receptor activity

2

0.002

  1. P value <0.05 was considered as threshold values of significant difference
  2. BP biological process, MF molecular function, CC cellular component, GO gene ontology
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Biological Research

ISSN: 0717-6287

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