Role of berberine in ameliorating Schistosoma mansoni-induced hepatic injury in mice

Biological Research

Table 2 Effect of berberine chloride on hepatic ALT, AST, ALP and γGT in male mice infected with S. mansoni

Experimental groups	ALT	AST	ALP	γ-GT
Experimental groups	(U/g)	(U/g)	(U/g)	(U/g)
Control	304 ± 1.8	229 ± 1.8	16 ± 1	25 ± 0.8
PZQ	315 ± 1.7^a	220 ± 4.5^a	13 ± 0.3^a	18 ± 1^a
BER	318 ± 1.4^a	255 ± 2.3^a	7.4 ± 0.4^a	15 ± 0.8^a
Infected	218 ± 3.6^a	125 ± 1^a	36 ± 1.2^a	48 ± 1.6^a
Infected + PZQ	263 ± 1.3^abc	146 ± 1.9 ^abc	17 ± 1^bc	16 ± 0.5^ac
Infected + BER	280 ± 2.8^abc	182 ± 2.4^abc	12 ± 1.6^abc	20 ± 0.6^abc

Values are means ± SD (n = 8). ^aSignificant difference as compared with Group I (p ≤ 0.05). ^bSignificant difference as compared with corresponding control group (p ≤ 0.05). ^cSignificant difference as compared with infected group (Group IV) (p ≤ 0.05).

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